If you say "DataGridView" then everyone is going to assume System.Windows.Forms.DataGridView. There's nothing in your first post to suggest that it's a web app or that you're using a third-party grid. Everything suggests WinForms, including the fact that you're using a System.Windows.Forms.BindingSource. There's no reason to ever use a BindingSource in a web app. As the namespace suggests, it's made for WinForms.
I've moved your thread to the Web Forms forum. I have no idea how your grid works as I've never heard of it, let alone used it. Maybe some other WebForms developer will know more.
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